Yaz (Drospirenone 3 Mg & Ethinylestradiol 0.02 Mg)
Synthetic st***dal compound with Estrogenic activity.Menopause (Hormone replacement therapy).Oral contraception.Threatened or habitual abortion.Dysmenorrhea.Dysfunctional uterine bleeding.Failure of ovarian development.Hirsuitism.Senile osteoporosis.Post menopausal osteoporosis.Breast cancer.Prostatic carcinoma.Suppression of post partum lactation.Senile vaginitis.Delayed puberty in girls.Acne (Not usually given). Drospirenone is used in combination with ethinyl estradiol as a birth control pill (oral contraceptive) in women. It is also used for a disease called premenstrual dysphoric disorder (PMDD; severe depression, irritability and tension just before menstruation), moderate acne, and to prevent osteoporosis in post-menopausal women.
How it works
Estrogens diffuse into their target cells and interact with a protein receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus, and the pituitary. Estrogens increase the hepatic synthesis of sex hormone binding globulin (SHBG), thyroid-binding globulin (TBG), and other serum proteins and suppress follicle-stimulating hormone (FSH) from the anterior pituitary. Drospirenone is progesterone, and together with estradiol, it can provide contraception by suppressing release of ovum (eggs) from your ovary, and interfering with other mechanisms that support occurrence of pregnancy. It suppresses the natural progesterone in the body, and thereby helps in PMDD and acne. Its mechanism of action in prevention of osteoporosis is not known.
What is Ethinyl estradiol and Drospirenone
Ethinyl estradiol and Drospirenone also sold under the brand name Yaz is a birth control pill. It works by preventing ovulation or the release of a female egg from the ovaries. It also causes changes in the cervical and uterine lining making the cervical mucus more viscous thereby making it harder for male sperms to reach the uterus and also for a fertilized egg to attach to the uterus wall.
This pill is used as a contraceptive method to prevent pregnancy. It is also used in treating moderate acne in women who are above 14 years of age and have started getting their periods, and who also wish to use contraception to avoid pregnancy.
Ethinyl estradiol/Drospirenone is also used for alleviating the symptoms of premenstrual dysphoric disorder (PMDD), such as depression, anxiety, irritability, concentration troubles, lethargy, changes in sleep patterns or appetite, muscle or joint pain, tender breasts, and weight gain.
This pill may also be given for treatments beside those listed above.
Important Information about Ethinyl estradiol and Drospirenone
Ethinyl estradiol and drospirenone is not recommended if you are pregnant or if you have recently delivered a baby. You must also not take this pill if you are suffering from any of these conditions: heart disease, out of control high blood pressure, blood clotting disorder, problems with circulation, problems in eyes or kidneys due to diabetes, unexplained vaginal bleeding, liver disease or liver cancer, migraine, if you are smoker and above 35, breast or uterine cancer, jaundice due to birth control pills, or a heart attack or a stroke in the recent past.
You may need to employ an alternate birth control method such as condoms or spermicide in the initial few days of starting with the pills or if you happen to miss a dose. Consult your doctor for more details.
Always store ethinyl estradiol and drospirenone pills in a cool and dry place away from heat, light, moisture, children and pets.
Before taking Ethinyl estradiol and Drospirenone
Before taking this pill, let your doctor know about all your medical history and if you are allergic to any medications or any ingredients in ethinyl estradiol and drospirenone. You must not take this medication if you have any of the conditions mentioned above.
To safely use this pill, tell your doctor if you have any of these condtions: high blood pressure, high cholesterol, obesity, depression in the past, hypothyroidism, gall bladder disease, diabetes, seizures, irregular periods, tuberculosis, or a history of fibrocystic disease in breasts, or an abnormal mammogram.
How do I take Ethinyl estradiol and Drospirenone?
Strictly follow the directions of your doctor while taking ethinyl estradiol and drospirenone. Any departure from the amount of prescribed dosage can cause harmful health effects and render the medication ineffective.
Start with the fist pill on the first day of your period or on the first Sunday after that. You may need an alternate birth control measure for the initial days of using these pills. You may use condoms or spermicide as back up contraception. You may need frequent doctor visits while taking these pills.
Take one pill every day orally and ensure that you don’t go more than 24 hours without a pill. Make a habit to take the pill at the same time every day. When the pills get over, start a new pack. Get a refill before the previous pack gets over as missing on a single dose can result in pregnancy.
You may get breakthrough bleeding during the first 3 months of starting this medication. See your doctor if it is persistent and turns heavy. Stop taking the pills if you experience severe vomiting and diarrhea and employ back up birth control method.
If you are scheduled for a surgery or any medical test or advised bed rest, you may need to discontinue this pill for some time. Any healthcare provider who treats you must know if you take the pills.
What if I miss a dose?
Missing even a single pill increases the risk of your pregnancy. So don’t skip a dose as far as possible.
If you happen to skip one active ethinyl estradiol and drospirenone pill, take two on the day that you remember. Then have one pill each day for the rest of the pack.
If you happen to skip two active pills consecutively in the first and second week, have two pills each day for two consecutive days. Then have one pill each day for the rest of the pack. Adopt back up contraception for at least one full week following the missed doses.
If you happen to skip two active pills consecutively in the third week, discard the rest of the pills and start a new pack the same day if you are a Day 1 starter. If you start on Sunday, continue taking a pill every day until Sunday. On Sunday, discard rest of the pack and open a new pack that day.
If you happen to skip three active pills consecutively in week 1, 2, or 3, discard the rest of the pack and open a new pack on the same day if you are a Day 1 starter. If you start on Sunday, continue taking a pill every day until Sunday. On Sunday, discard away rest of the pack and start a new pack that day.
What if I Overdose?
If you overdose on ethinyl estradiol and drospirenone pills, you may experience symptoms like nausea, vomiting, and vaginal bleeding.
Things to avoid while taking Ethinyl estradiol and Drospirenone
If you are a smoker and over 35 years of age, taking ethinyl estradiol and drospirenone pills can increase the risk of blood clot, stroke, or heart attack. These pills may be more likely to cause blood clots than other types of contraceptive pills.
This pill will not protect you from STDs so it is wise to stay away from unsafe sexual practices.
Ethinyl estradiol and Drospirenone Side Effects
Many people may not experience any side effects due to ethinyl estradiol and drospirenone pills. However some of the less serious side effects of pills are vomiting, nausea, headache, bloating, breast tenderness, swelling in limbs (fluid retention), unexpected weight changes, vaginal spotting, missed or irregular periods. If any of these symptoms continue for a longer period or deteriorate, get urgent medical help.
Some of the rare and serious side effects of this medication are blood clotting disorders like deep vein thrombosis, heart attack, stroke, or embolism; sudden breath shortness; pain in chest, jaw or left arm; unexpected sweating; confusion bloody cough; sudden giddiness or fainting; migraines; vision or speech problems. Contact your doctor right away if you get these serious conditions.
The conditions listed above are non exhaustive and you may experience other non serious or life threatening conditions. Get immediate and urgent medical in such cases.
Interaction with other Drugs
Certain medications can interfere with ethinyl estradiol and drospirenone. Let your doctor know about all present medications and your entire medical history.
Some of the drugs than can interact with this medication are: aromatase inhibitors (anastrazole, exemestane), raloxifene, sodium tetradecyl sulfate, tamoxifen, tizanidine.
Drospirenone may increase your blood potassium level. Some other medicines can also increase the blood potassium levels like aliskiren, ACE inhibitors like enalapril/lisinopril, angiotensin receptor blockers like losartan/valsartan, heparin, NSAIDs such as ibuprofen/naproxen, potassium-sparing "water pills"/diuretics like eplerenone/spironolactone/triamterene). Your doctor will know about the interactions and prescribe accordingly.
The above list of interactions is non exhaustive and there may be other interactions which your doctor may know. Always consult your doctor for proper medical care.
|Strength||3 mg + 0.02 mg|
|Generic Name||Drospirenone and Ethinyl Estradiol|
|Manufacturer||Bayer Schering Pharma|
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