Tacrolimus is used after transplantation of organs such as heart, liver, kidney or other organs so that the body does not reject the new organ. It is also used for certain skin diseases.
How it works
Tacrolimus belongs to a category of drugs called as immunosuppressant. It prevents the body’s immune system from attacking the newly transplanted organ such as liver, heart, or kidney. This also helps in resolution of skin diseases due to altered immune function.
Common side effects
vascular diseases, changes in liver enzyme levels, cough, leucopenia, calcium, alopecia, edema, nasal congestion, hallucinations, mood changes, abdominal pain, renal impairment .Common: Vomiting, dyspepsia, bloating, magnesium, muscle pain, insomnia, increase in weight, itching, depression, skin rashes, cholesterol, acne, Very common: Urge to vomit, diarrhea, tremors, thrombocytopenia, increased levels of potassium, vision problems, cramps, anxiety, seizures, anemia, or uric acid in the blood., headache, tinnitus, flatulence, weakness.
Take tacrolimus on empty stomach or 2-3 hours after a meal.
Do not take tacrolimus if you are allergic to it or to any other content in the medicine; or to sirolimus or other macrolide antibiotics (erythromycin, clarithromycin).
Doctor’s advice should be considered in case of patients with following history of disease conditions: liver problems, abnormal electrical signaling of the heart (QT interval prolongation), or diarrhea lasting for more than a day; abdominal pain, with or without vomiting, nausea, chills and fever.
Avoid using tacrolimus if you are pregnant or planning to become pregnant or breast-feeding a baby.
Limit exposure to the sun while taking the drug. Wear protective clothing and use sunscreen when stepping out in the sun, to prevent skin cancer.
Do not drive or operate heavy machinery while taking tacrolimus as it may cause dizziness.
Frequently asked questions
Q. Is tacrolimus safe in pregnancy?
Tacrolimus may cause harm to the fetus. Hence, it is not advisable to take it during pregnancy without consulting your doctor.
Q. Is tacrolimus a st***d?
Tacrolimus is an immunosuppressant drug. It is not a st***d drug.
Q. Is tacrolimus nephrotoxic or cytotoxic?
Tacrolimus may cause destruction of certain types of cells (cytotoxic) and may impair kidney function (nephrotoxic). Patients should follow the advice of the doctor regarding its use.
Q. Is tacrolimus the same as Prograf?
Yes. Progarf is a branded form of tacrolimus available in the market.
Q. Is tacrolimus safe?
Yes. Tacrolimus is relatively safe if used as recommended. In case of any side-effects, consult your doctor.
Q. Can I take tacrolimus with omeprazole?
Omeprazole may increase the blood levels of tacrolimus. It can be taken with omeprazole only if prescribed by your doctor.
Q. Does tacrolimus cause diabetes, hair loss, tiredness, or depression?
Tacrolimus may cause diabetes, hair loss, tiredness, or depression. If you experience any such symptoms, please consult your doctor.
0.1% (10 gm)
Glenmark Pharma, India
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Jan 31, 2016
it's good one
Some side effects...they've been manageable. Keeping a positive attitude and having a support group has been beneficial.
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