Siromus 1mg (sirolimus)
What is Siromus (sirolimus)?
Indications: Siromus (Sirolimus) is an immunosuppressant used to prevent organ rejection after a kidney transplant. Siromus (Sirolimus) may also be used to treat other conditions as determined by your doctor.
What is the most important information I should know about Siromus (sirolimus)?
You should not use sirolimus if you have ever had a lung transplant or liver transplant. Sirolimus can lower blood cells that help fight infection, and may lead to serious conditions including cancer, severe brain infection causing disability or death, or a viral infection causing kidney transplant failure.
What should I discuss with my healthcare provider before taking Siromus (sirolimus)?
Sirolimus may increase your risk of developing lymphoma or other forms of cancer. Talk with your doctor about your specific risk. You should not use this medicine if you are allergic to sirolimus, or if you have ever had a lung transplant or liver transplant. To make sure sirolimus is safe for you, tell your doctor if you have: high cholesterol or triglycerides; cytomegalovirus (CMV); liver disease; or a family history of skin cancer (melanoma).
It is not known whether this medicine will harm an unborn baby. Do not use sirolimus if you are pregnant. Use effective birth control to prevent pregnancy while you are taking sirolimus, and for at least 12 weeks after your treatment ends. It is not known whether sirolimus passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine. Sirolimus should not be given to a child younger than 13 years old.
How should I take Siromus (sirolimus)?
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended. Sirolimus is usually taken once a day. If you also take cyclosporine, wait at least 4 hours after your cyclosporine dose before you take sirolimus. You may take sirolimus with or without food, but take it the same way every time. Do not crush, chew, or break a sirolimus tablet. Tell your doctor if you have trouble swallowing the tablet whole. Sirolimus oral liquid must be mixed in a glass or plastic cup with at least 2 ounces (1/4 cup) of water or orange juice. Do not use any other juices or liquids to mix this medicine. Stir the mixture and drink all of it right away. Then add at least 4 ounces (1/2 cup) more water or orange juice to the same glass, stir again and drink right away.
Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. Sirolimus can lower blood cells that help fight infection, and may cause you to produce too much of a certain type of white blood cell. This can lead to serious conditions including cancer, severe brain infection causing disability or death, or a viral infection causing kidney transplant failure. Your blood will need to be tested often. Your kidney function will also need to be tested. Your sirolimus dosing schedule may be delayed based on the results of these tests. You should not stop using sirolimus without your doctor's advice. Stopping suddenly could make your condition worse.
Store sirolimus tablets at room temperature, away from heat, moisture, and light. Store sirolimus liquid in the refrigerator. Do not freeze. You may notice a slight haze to the liquid after it has been refrigerated. This haze will not affect the medication, and should disappear when the liquid reaches room temperature. If you are using sirolimus oral liquid with a disposable syringe, you may store a loaded syringe in the carrying case provided. Keep the case at room temperature and use the medicine within 24 hours. Use a disposable syringe only once and then throw it away.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Siromus (sirolimus)?
Avoid exposure to sunlight or tanning beds. Sirolimus may increase your risk of skin cancer. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection. Avoid getting sirolimus oral liquid on your skin. Wash the skin with soap and water if this happens. If this medicine gets into your eyes, rinse them with plain water. Grapefruit and grapefruit juice may interact with sirolimus and could lead to potentially dangerous effects. Do not mix this medicine with grapefruit juice. Avoid eating grapefruit or drinking grapefruit juice while you are taking sirolimus. Do not receive a "live" vaccine while using sirolimus. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.
What are the side effects of Generic for Siromus?
Like other medicines, Generic for Siromus can cause some side effects. If they do occur, the side effects of Generic for Siromus are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately. It is pertinent to note that side effects of Generic for Siromus cannot be anticipated. If any side effects of Generic for Siromus develop or change in intensity, the doctor should be informed as soon as possible. Generic for Siromus can cause side effects such as backache, diarrhea, blurred vision, joint pain, shaking, dry mouth, and runny nose. This is not a complete list of all side effects. Do concur with your doctor and follow his directions completely when you are taking Generic for Siromus
What other drugs will affect Siromus (sirolimus)?
Many drugs can interact with sirolimus. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially: bromocriptine (Cycloset, Parlodel); danazol; St. John's wort; tacrolimus; cholesterol-lowering medication; an antibiotic or antifungal medicine; antiviral medicine to treat HIV or hepatitis C; heart or blood pressure medication; medicine to reduce stomach acid or treat an ulcer; or seizure medicine.
This list is not complete and many other drugs can interact with sirolimus. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.
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What is Generic for Siromus used for?
Generic for Siromus (Sirolimus) is used to prevent rejection of a kidney transplant. It works by suppressing your body's immune system that can reject a transplanted organ. This medication belongs to a class of drugs known as immunosuppressants. This medicine may also be used to treat other conditions as determined by your doctor.
What are the questions to ask your doctor before taking Generic for Siromus?
Is it possible for me to take Generic for Siromus with other drugs?
Should certain beverages, foods and other products be avoided when I take Generic for Siromus?
What are the possible drug interactions of Generic for Siromus?
How will Generic for Siromus work in my body?
How should Generic for Siromus be taken?
How to reduce the risk of Generic for Siromus drug interactions and side effects?
|Manufacturer||Zydus Pharma, India|
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