Donecept 10mg (Donepezil)
Uses of Donecept
Donepezil hydrochloride is used to treat the symptoms of dementia (which includes increasing memory loss, confusion and behavioral changes) in people diagnosed as having mild and moderately severe Alzheimer’s disease.
How Donecept works?
Donepezil hydrochloride belongs to a group of medicines called acetylcholinesterase inhibitors. Donepezil increases the levels of a substance (acetylcholine) in the brain involved in memory function by slowing down the breakdown of acetylcholine.
What is Donecept?
Donecept (donepezil) improves the function of nerve cells in the brain. It works by preventing the breakdown of a chemical called acetylcholine (ah SEET il KOE leen). People with dementia usually have lower levels of this chemical, which is important for the processes of memory, thinking, and reasoning.
Donecept is used to treat mild to moderate dementia caused byAlzheimer's disease.
Donecept is not a cure for Alzheimer's disease. This condition will progress over time, even in people who take donepezil.
Important information about Donecept
Before taking Donecept, tell your doctor if you have a heart rhythm disorder such as "sick sinus syndrome" (slow heartbeats), an enlarged prostate, urination problems, asthma, obstructive pulmonary disease, or a seizure disorder such as epilepsy.
If you need to have any type of surgery, tell the surgeon ahead of time that you are taking Donecept.
Donecept can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
You should inform your doctor in advance before taking Donepezil Alzheimer's medication (Donecept, Donep) if you have any of these conditions: heart disease, a heart rhythm disorder, urination problems, stomach ulcers or bleeding, asthma or chronic obstructive pulmonary disease (COPD), a seizure disorder, asthma, kidney disease, or liver disease.
Immediately stop using Donepezil medication and seek medical attention if you experience chest pain, low heart rate, bloody stools, coughing up blood, reduced urination, weakness, confusion, extreme thirst, or hot or dry skin.
There are several drugs which can interact with Donepezil. Notify your doctor about all medications and related products (OTC vitamin pill, herbal products and others) which you may be using prior to taking this medication.
If you are scheduled for a surgery, you may be required to suspend taking Donepezil for a short period. Let your surgeon know well in advance that you are taking this medication. Donepezil may impact your thinking capabilities and reflexes. So take extra care while indulging in activities that require a high degree of mental awareness and thinking such as driving.
Donepezil is a FDA pregnancy category C drug. This medication may be harmful to unborn baby if taken while being pregnant. Notify your doctor of you pregnancy or any plans to become pregnant. It is not known if Donepezil can pass into breast milk and harm a nursing baby. Do not take this medication without asking a doctor if you are breast feeding a baby.
Dosage and Administration of Donecept
Dosing In Mild To Moderate Alzheimer's Disease
The recommended starting dosage of Donecept is 5 mg administered once per day in the evening, just prior to retiring. The maximum recommended dosage of Donecept in patients with mild to moderate Alzheimer's disease is 10 mg per day. A dose of 10 mg should not be administered until patients have been on a daily dose of 5 mg for 4 to 6 weeks.
Dosing In Moderate To Severe Alzheimer's Disease
The recommended starting dosage of Donecept is 5 mg administered once per day in the evening, just prior to retiring. The maximum recommended dosage of Donecept in patients with moderate to severe Alzheimer's disease is 23 mg per day. A dose of 10 mg should not be administered until patients have been on a daily dose of 5 mg for 4 to 6 weeks. A dose of 23 mg per day should not be administered until patients have been on a daily dose of 10 mg for at least 3 months.
Donecept should be taken in the evening, just prior to retiring. Donecept can be taken with or without food.
The Donecept 23 mg tablet should not be split, crushed, or chewed.
Allow Donecept ODT to dissolve on the tongue and follow with water.
Before taking Donecept (Donepezil)
Before taking Donepezil (Donecept, Donep), take care of all precautions mentioned above and discuss them with your doctor.
How should I take Donecept (Donepezil)?
Take Donepezil Alzheimerâ€™s medication (Donecept, Donep) strictly according to your doctorâ€™s direction or according to the instructions on the medication label. Do not alter the dosage unless your doctor advises you to do so. Your doctor may occasionally change the dosage to get the maximum benefit out of the medication. Also, do not take this medication after the prescribed period is over.
Donepezil is normally taken at bedtime. Take the normal oral tablet with a full glass of water. Always store Donepezil medication in a cool and dry place.
What if I miss a dose?
If you miss a dose of Donepezil, take it as soon as you remember. Donâ€™t take the missed dose if the time to take the next dose is almost up. Taking multiple doses near to each other can lead to excess medication in your body which can be harmful.
What if I overdose?
In case of an overdose of Donepezil, get emergency medical attention or call the Doctor immetiately. Overdose may lead to symptoms like severe nausea, vomiting, cramps in stomach, muscle weakness or spasm, watery eyes, drooling, increased urination or bowel movements, sweating, slow heart rate, light headedness, or seizures.
Things and Activities to avoid while taking Donecept (Donepezil)
Donepezil may impact your thinking capabilities and reflexes. So take extra care while indulging in activities that require a high degree of mental awareness and thinking such as driving.
Side Effects due to Donecept (Donepezil)
You may witness or experience some side effects while taking Donepezil (Donecept, Donep). Some of the side effects due to Donepezil are nausea, vomiting, diarrhea, dizziness, appetite loss, or weight loss. Seek emergency medical attention if any of these effects persist for a longer period or deteriorate further.
Any serious side effect is rare but get in touch with your doctor immediately if you have any of these serious side effects of Donepezil: fainting, unusually slow heartbeat, difficulty while urinating, seizures, black or bloody stools, bloody vomit that looks like coffee grounds, stomach pain/abdominal pain, or irregular heartbeat
These are not the only side effects of Donepezil medication. There may be others. Contact your doctor right away if you experience any serious side effects or if your condition worsens after taking Donepezil.
Interaction with other drugs
Some drugs can interact with Donepezil. Let your doctor know in advance if you are already using any of these interacting drugs: erythromycin,
galantamine, paroxetine, antifungal medicine like ketoconazole or others, rivastigmine, atropine, belladonna, scopolamine, bladder or urinary medicines such as darifenacin, flavoxate, oxybutynin or others, bronchodilators such as ipratropium or tiotropium, irritable bowel medicines such as dicyclomine, hyoscyamine, or propantheline, ulcer medications like mepenzolate or glycopyrrolate, or NSAIDs such as ibuprofen, celecoxib, naproxen, or others.
The list of drugs mentioned here in this guide is not a complete one and there may be other interacting drugs. Share the list of all present medication which you may be using with your doctor. Never start a new medication on your own.
Expert advice for Donecept
- Do not take donepezil hydrochloride, if you are allergic to donepezil hydrochloride or any of the other ingredients of this medicine.
- Avoid using donepezil hydrochloride, if you are breastfeeding.
- Doctor’s advice should be considered in case of patients with following history of disease conditions: stomach or duodenal ulcers; seizures (fits) or convulsions; heart condition (irregular or very slow heart beat); asthma or other long term lung disease; liver problems or hepatitis; urine or mild kidney disease.
- Do not use donepezil hydrochloride, if you are pregnant.
- Donepezil hydrochloride is not intended for use in children and adolescents younger than 18 years.
- Donepezil hydrochloride should not be taken with alcohol because alcohol may change its effect.
- Do not drive or operate machinery.
Frequently asked questions
Q. What is donepezil hydrochloride/ what is donepezil hydrochloride used for/ what does donepezil hydrochloride do?
Donepezil hydrochloride belongs to a group of medicines called acetylcholinesterase inhibitors and is used to treat the symptoms of dementia (which includes increasing memory loss, confusion and behavioral changes) in people diagnosed as having mild and moderately severe Alzheimer’s disease.
Q. Does donepezil Hcl work?
Donepezil hydrochloride does work, but its effectiveness can be different based on individual response.
|Manufacturer||Cipla Pharma, India|
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